Products & Services / Immuno-Oncology / ODISEI ONC

ODISEI ONC

ODISEI ONC is a multi-level oncology drug evaluation solution designed to model tumor–immune system interactions. Built on patient-derived organoids (PDOs) that retain the genetic and phenotypic features of original tumors, the platform recreates the tumor microenvironment with increasing immune complexity from ODISEI ONC 1.0 to 4.0.

From basic cancer organoid cultures to advanced co-culture models with immune cells and cytokine signaling, ODISEI ONC enables precise evaluation of tumor–immune interactions, immune evasion, and therapeutic response.

Application Note

Immune checkpoint inhibitors regulate interactions between cancer cells and immune cells, enabling the immune system to recognize and eliminate tumor cells. To evaluate their effects accurately, ODISEI uses a patient-specific co-culture platform that combines cancer organoids and immune cells derived from the same patient.
This approach allows researchers to observe immune-mediated cancer cell killing in a physiologically relevant environment and assess the efficacy of immune checkpoint inhibitors with greater clinical relevance.

Example of efficacy evaluation

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Immuno-Oncology

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